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The rasGAP-binding protein, Dok-1, mediates activin signaling via serine/threonine kinase receptors

The rasGAP-binding protein, Dok-1, mediates activin signaling via serine/threonine kinase receptors

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_125939

The rasGAP-binding protein, Dok-1, mediates activin signaling via serine/threonine kinase receptors

About this item

Full title

The rasGAP-binding protein, Dok-1, mediates activin signaling via serine/threonine kinase receptors

Publisher

Chichester, UK: John Wiley & Sons, Ltd

Journal title

The EMBO journal, 2002-04, Vol.21 (7), p.1684-1694

Language

English

Formats

Publication information

Publisher

Chichester, UK: John Wiley & Sons, Ltd

More information

Scope and Contents

Contents

Activins, members of the transforming growth factor‐β family, are pleiotropic growth and differentiation factors. Activin A induces B‐cell apoptosis. To identify the genes responsible for activin‐induced apoptosis, we performed retrovirus‐mediated gene trap screening in a mouse B‐cell line. We identified the rasGAP‐binding protein Dok‐1 (p62) as an...

Alternative Titles

Full title

The rasGAP-binding protein, Dok-1, mediates activin signaling via serine/threonine kinase receptors

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_125939

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_125939

Other Identifiers

ISSN

0261-4189,1460-2075

E-ISSN

1460-2075

DOI

10.1093/emboj/21.7.1684

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