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PA200, a nuclear proteasome activator involved in DNA repair

PA200, a nuclear proteasome activator involved in DNA repair

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_126083

PA200, a nuclear proteasome activator involved in DNA repair

About this item

Full title

PA200, a nuclear proteasome activator involved in DNA repair

Publisher

Chichester, UK: John Wiley & Sons, Ltd

Journal title

The EMBO journal, 2002-07, Vol.21 (13), p.3516-3525

Language

English

Formats

Publication information

Publisher

Chichester, UK: John Wiley & Sons, Ltd

More information

Scope and Contents

Contents

We have identified a novel 200 kDa nuclear protein that activates the proteasome. The protein, which we call PA200, has been purified to homogeneity from bovine testis and has been shown to activate proteasomal hydrolysis of peptides, but not proteins. Following γ‐irradiation of HeLa cells the uniform nuclear distribution of PA200 changes to a stri...

Alternative Titles

Full title

PA200, a nuclear proteasome activator involved in DNA repair

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_126083

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_126083

Other Identifiers

ISSN

0261-4189,1460-2075

E-ISSN

1460-2075

DOI

10.1093/emboj/cdf333

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