The Case for Selection at CCR5-Δ32
The Case for Selection at CCR5-Δ32
About this item
Full title
Author / Creator
Publisher
San Francisco, USA: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
San Francisco, USA: Public Library of Science
Subjects
More information
Scope and Contents
Contents
The C-C chemokine receptor 5, 32 base-pair deletion
(CCR5-
Δ
32)
allele confers strong resistance to infection by the AIDS virus HIV. Previous studies have suggested that
CCR5-
Δ
32
arose within the past 1,000 y and rose to its present high frequency (5%–14%) in Europe as a result of strong positive selection, perhaps by suc...
Alternative Titles
Full title
The Case for Selection at CCR5-Δ32
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1275522
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1275522
Other Identifiers
ISSN
1545-7885,1544-9173
E-ISSN
1545-7885
DOI
10.1371/journal.pbio.0030378