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The Case for Selection at CCR5-Δ32

The Case for Selection at CCR5-Δ32

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1275522

The Case for Selection at CCR5-Δ32

About this item

Full title

The Case for Selection at CCR5-Δ32

Publisher

San Francisco, USA: Public Library of Science

Journal title

PLoS biology, 2005-11, Vol.3 (11), p.e378

Language

English

Formats

Publication information

Publisher

San Francisco, USA: Public Library of Science

More information

Scope and Contents

Contents

The C-C chemokine receptor 5, 32 base-pair deletion
(CCR5-
Δ
32)
allele confers strong resistance to infection by the AIDS virus HIV. Previous studies have suggested that
CCR5-
Δ
32
arose within the past 1,000 y and rose to its present high frequency (5%–14%) in Europe as a result of strong positive selection, perhaps by suc...

Alternative Titles

Full title

The Case for Selection at CCR5-Δ32

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1275522

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1275522

Other Identifiers

ISSN

1545-7885,1544-9173

E-ISSN

1545-7885

DOI

10.1371/journal.pbio.0030378

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