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Analysis of Scc1-deficient cells defines a key metaphase role of vertebrate cohesin in linking siste...

Analysis of Scc1-deficient cells defines a key metaphase role of vertebrate cohesin in linking siste...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1298988

Analysis of Scc1-deficient cells defines a key metaphase role of vertebrate cohesin in linking sister kinetochores

About this item

Full title

Analysis of Scc1-deficient cells defines a key metaphase role of vertebrate cohesin in linking sister kinetochores

Publisher

Chichester, UK: John Wiley & Sons, Ltd

Journal title

EMBO reports, 2004-02, Vol.5 (2), p.167-171

Language

English

Formats

Publication information

Publisher

Chichester, UK: John Wiley & Sons, Ltd

More information

Scope and Contents

Contents

Cleavage of the cohesin subunit Scc1p/Mcd1p/Rad21 permits sister chromatid separation and is considered to trigger anaphase onset. It has also been suggested that the cohesin complex is essential for chromosome condensation and for assembling fully functional kinetochores. Here, we used vertebrate cells conditionally deficient in
Scc1
to prob...

Alternative Titles

Full title

Analysis of Scc1-deficient cells defines a key metaphase role of vertebrate cohesin in linking sister kinetochores

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1298988

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1298988

Other Identifiers

ISSN

1469-221X

E-ISSN

1469-3178,1469-221X

DOI

10.1038/sj.embor.7400077

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