Analysis of Scc1-deficient cells defines a key metaphase role of vertebrate cohesin in linking siste...
Analysis of Scc1-deficient cells defines a key metaphase role of vertebrate cohesin in linking sister kinetochores
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Chichester, UK: John Wiley & Sons, Ltd
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English
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Chichester, UK: John Wiley & Sons, Ltd
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Contents
Cleavage of the cohesin subunit Scc1p/Mcd1p/Rad21 permits sister chromatid separation and is considered to trigger anaphase onset. It has also been suggested that the cohesin complex is essential for chromosome condensation and for assembling fully functional kinetochores. Here, we used vertebrate cells conditionally deficient in
Scc1
to prob...
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Full title
Analysis of Scc1-deficient cells defines a key metaphase role of vertebrate cohesin in linking sister kinetochores
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1298988
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1298988
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ISSN
1469-221X
E-ISSN
1469-3178,1469-221X
DOI
10.1038/sj.embor.7400077