A short synthetic peptide inhibits signal transduction, migration and angiogenesis mediated by Tie2...
A short synthetic peptide inhibits signal transduction, migration and angiogenesis mediated by Tie2 receptor
About this item
Full title
Author / Creator
Publisher
Chichester, UK: John Wiley & Sons, Ltd
Journal title
Language
English
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Publication information
Publisher
Chichester, UK: John Wiley & Sons, Ltd
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Scope and Contents
Contents
Tie2, an endothelial cell‐specific receptor kinase, has an important role in tumour angiogenesis. In an attempt to identify peptides that specifically interact with and block the Tie2 pathway, a phage‐displayed peptide library was screened on a recombinant Tie2 receptor. One peptide, NLLMAAS, completely abolished the binding to Tie2 of both angiopo...
Alternative Titles
Full title
A short synthetic peptide inhibits signal transduction, migration and angiogenesis mediated by Tie2 receptor
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1299011
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1299011
Other Identifiers
ISSN
1469-221X
E-ISSN
1469-3178
DOI
10.1038/sj.embor.7400100
