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Ca(2+) channel inactivation heterogeneity reveals physiological unbinding of auxiliary beta subunits

Ca(2+) channel inactivation heterogeneity reveals physiological unbinding of auxiliary beta subunits

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1301494

Ca(2+) channel inactivation heterogeneity reveals physiological unbinding of auxiliary beta subunits

About this item

Full title

Ca(2+) channel inactivation heterogeneity reveals physiological unbinding of auxiliary beta subunits

Publisher

United States

Journal title

Biophysical journal, 2001-07, Vol.81 (1), p.89-96

Language

English

Formats

Publication information

Publisher

United States

More information

Scope and Contents

Contents

Voltage gated Ca(2+) channel (VGCC) auxiliary beta subunits increase membrane expression of the main pore-forming alpha(1) subunits and finely tune channel activation and inactivation properties. In expression studies, co-expression of beta subunits also reduced neuronal Ca(2+) channel regulation by heterotrimeric G protein. Biochemical studies sug...

Alternative Titles

Full title

Ca(2+) channel inactivation heterogeneity reveals physiological unbinding of auxiliary beta subunits

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1301494

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1301494

Other Identifiers

ISSN

0006-3495

E-ISSN

1542-0086

DOI

10.1016/S0006-3495(01)75682-2

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