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Role of the Proposed Pore-Forming Segment of the Ca2+ Release Channel (Ryanodine Receptor) in Ryanod...

Role of the Proposed Pore-Forming Segment of the Ca2+ Release Channel (Ryanodine Receptor) in Ryanod...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1302034

Role of the Proposed Pore-Forming Segment of the Ca2+ Release Channel (Ryanodine Receptor) in Ryanodine Interaction

About this item

Full title

Role of the Proposed Pore-Forming Segment of the Ca2+ Release Channel (Ryanodine Receptor) in Ryanodine Interaction

Publisher

United States

Journal title

Biophysical journal, 2002-05, Vol.82 (5), p.2436-2447

Language

English

Formats

Publication information

Publisher

United States

More information

Scope and Contents

Contents

In earlier studies we showed that point mutations introduced into the proposed pore-forming segment, GVRAGGGIGD (amino acids 4820-4829), of the mouse cardiac ryanodine receptor reduced or abolished high affinity [3H]ryanodine binding. Here we investigate the effects of these mutations on the affinity and dissociation properties of [3H]ryanodine bin...

Alternative Titles

Full title

Role of the Proposed Pore-Forming Segment of the Ca2+ Release Channel (Ryanodine Receptor) in Ryanodine Interaction

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1302034

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1302034

Other Identifiers

ISSN

0006-3495

E-ISSN

1542-0086

DOI

10.1016/S0006-3495(02)75587-2

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