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Permeant Cations and Blockers Modulate pH Gating of ROMK Channels

Permeant Cations and Blockers Modulate pH Gating of ROMK Channels

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1302669

Permeant Cations and Blockers Modulate pH Gating of ROMK Channels

About this item

Full title

Permeant Cations and Blockers Modulate pH Gating of ROMK Channels

Publisher

United States: Elsevier Inc

Journal title

Biophysical journal, 2003-02, Vol.84 (2), p.910-921

Language

English

Formats

Publication information

Publisher

United States: Elsevier Inc

More information

Scope and Contents

Contents

External potassium (K) activates the inward rectifier ROMK (K
ir1.1) by altering the pH gating of the channel. The present study examines this link between external K and internal pH sensitivity using both the two-electrode voltage clamp and the perfused, cut-open
Xenopus oocyte preparation. Elevating extracellular K from 1
mM to 10
mM...

Alternative Titles

Full title

Permeant Cations and Blockers Modulate pH Gating of ROMK Channels

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1302669

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1302669

Other Identifiers

ISSN

0006-3495

E-ISSN

1542-0086

DOI

10.1016/S0006-3495(03)74908-X

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