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Investigation of Pathways for the Low-pH Conformational Transition in Influenza Hemagglutinin

Investigation of Pathways for the Low-pH Conformational Transition in Influenza Hemagglutinin

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1302762

Investigation of Pathways for the Low-pH Conformational Transition in Influenza Hemagglutinin

About this item

Full title

Investigation of Pathways for the Low-pH Conformational Transition in Influenza Hemagglutinin

Publisher

United States: Elsevier Inc

Journal title

Biophysical journal, 2003-03, Vol.84 (3), p.1926-1939

Language

English

Formats

Publication information

Publisher

United States: Elsevier Inc

More information

Scope and Contents

Contents

Targeted molecular dynamics simulations were used to study the conformational transition of influenza hemagglutinin (HA) from the native conformation to putative fusogenic or postfusion conformations populated at low pH. Three pathways for this conformational change were considered. Complete dissociation of the globular domains of HA was observed i...

Alternative Titles

Full title

Investigation of Pathways for the Low-pH Conformational Transition in Influenza Hemagglutinin

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1302762

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1302762

Other Identifiers

ISSN

0006-3495

E-ISSN

1542-0086

DOI

10.1016/S0006-3495(03)75001-2

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