Investigation of Pathways for the Low-pH Conformational Transition in Influenza Hemagglutinin
Investigation of Pathways for the Low-pH Conformational Transition in Influenza Hemagglutinin
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Publisher
United States: Elsevier Inc
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Language
English
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Publisher
United States: Elsevier Inc
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Scope and Contents
Contents
Targeted molecular dynamics simulations were used to study the conformational transition of influenza hemagglutinin (HA) from the native conformation to putative fusogenic or postfusion conformations populated at low pH. Three pathways for this conformational change were considered. Complete dissociation of the globular domains of HA was observed i...
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Full title
Investigation of Pathways for the Low-pH Conformational Transition in Influenza Hemagglutinin
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1302762
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1302762
Other Identifiers
ISSN
0006-3495
E-ISSN
1542-0086
DOI
10.1016/S0006-3495(03)75001-2