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Effects of Permeant Ion Concentrations on the Gating of L-Type Ca2+ Channels in Hair Cells

Effects of Permeant Ion Concentrations on the Gating of L-Type Ca2+ Channels in Hair Cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1302902

Effects of Permeant Ion Concentrations on the Gating of L-Type Ca2+ Channels in Hair Cells

About this item

Full title

Effects of Permeant Ion Concentrations on the Gating of L-Type Ca2+ Channels in Hair Cells

Publisher

United States: Elsevier Inc

Journal title

Biophysical journal, 2003-05, Vol.84 (5), p.3457-3469

Language

English

Formats

Publication information

Publisher

United States: Elsevier Inc

More information

Scope and Contents

Contents

We determined the gating and permeation properties of single L-type Ca2+ channels, using hair cells and varying concentrations (5–70mM) of the charge carriers Ba2+ and Ca2+. The channels showed distinct gating modes with high- and low-open probability. The half-activation voltage (V1/2) shifted in the hyperpolarizing direction from high to low perm...

Alternative Titles

Full title

Effects of Permeant Ion Concentrations on the Gating of L-Type Ca2+ Channels in Hair Cells

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1302902

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1302902

Other Identifiers

ISSN

0006-3495

E-ISSN

1542-0086

DOI

10.1016/S0006-3495(03)70066-6

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