Molecular Dynamics Analysis of Structural Factors Influencing Back Door Pi Release in Myosin
Molecular Dynamics Analysis of Structural Factors Influencing Back Door Pi Release in Myosin
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United States: Biophysical Society
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Language
English
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United States: Biophysical Society
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Contents
The back door has been proposed to be an exit pathway from the myosin active site for phosphate (P(i)) generated by adenosine 5'-triphosphate hydrolysis. We used molecular dynamics simulations to investigate the interaction of P(i) with the back door and the plausibility of P(i) release via this route. Molecular dynamics simulations were performed...
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Full title
Molecular Dynamics Analysis of Structural Factors Influencing Back Door Pi Release in Myosin
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1304280
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1304280
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ISSN
0006-3495
E-ISSN
1542-0086
DOI
10.1529/biophysj.103.037390