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Inhibition of intracellular hepatitis C virus replication by synthetic and vector-derived small inte...

Inhibition of intracellular hepatitis C virus replication by synthetic and vector-derived small inte...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1319196

Inhibition of intracellular hepatitis C virus replication by synthetic and vector-derived small interfering RNAs

About this item

Full title

Inhibition of intracellular hepatitis C virus replication by synthetic and vector-derived small interfering RNAs

Publisher

Chichester, UK: John Wiley & Sons, Ltd

Journal title

EMBO reports, 2003-06, Vol.4 (6), p.602-608

Language

English

Formats

Publication information

Publisher

Chichester, UK: John Wiley & Sons, Ltd

More information

Scope and Contents

Contents

Small interfering RNAs (siRNAs) efficiently inhibit gene expression by RNA interference. Here, we report efficient inhibition, by both synthetic and vector‐derived siRNAs, of hepatitis C virus (HCV) replication, as well as viral protein synthesis, using an HCV replicon system. The siRNAs were designed to target the 5′ untranslated region (5′ UTR) o...

Alternative Titles

Full title

Inhibition of intracellular hepatitis C virus replication by synthetic and vector-derived small interfering RNAs

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1319196

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1319196

Other Identifiers

ISSN

1469-221X

E-ISSN

1469-3178,1469-221X

DOI

10.1038/sj.embor.embor840

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