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PTEN Negatively Regulates Neural Stem Cell Self-Renewal by Modulating G₀-G₁ Cell Cycle Entry

PTEN Negatively Regulates Neural Stem Cell Self-Renewal by Modulating G₀-G₁ Cell Cycle Entry

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1325011

PTEN Negatively Regulates Neural Stem Cell Self-Renewal by Modulating G₀-G₁ Cell Cycle Entry

About this item

Full title

PTEN Negatively Regulates Neural Stem Cell Self-Renewal by Modulating G₀-G₁ Cell Cycle Entry

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2006-01, Vol.103 (1), p.111-116

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Previous studies have demonstrated that a small subpopulation of brain tumor cells share key characteristics with neural stem/ progenitor cells in terms of phenotype and behavior. These findings suggest that brain tumors might contain "cancer stem cells" that are critical for tumor growth. However, the molecular pathways governing such stem cell-li...

Alternative Titles

Full title

PTEN Negatively Regulates Neural Stem Cell Self-Renewal by Modulating G₀-G₁ Cell Cycle Entry

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1325011

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1325011

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0509939103

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