FRNK blocks v-Src-stimulated invasion and experimental metastases without effects on cell motility o...
FRNK blocks v-Src-stimulated invasion and experimental metastases without effects on cell motility or growth
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Publisher
Chichester, UK: John Wiley & Sons, Ltd
Journal title
Language
English
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Publisher
Chichester, UK: John Wiley & Sons, Ltd
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Scope and Contents
Contents
Focal adhesion kinase (FAK) was first identified as a viral Src (v‐Src) substrate, but the role of FAK in Src transformation events remains undefined. We show that stable expression of the FAK C‐terminal domain (termed FRNK) in v‐Src‐transformed NIH 3T3 fibroblasts inhibited cell invasion through Matrigel and blocked experimental metastases in nude...
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Full title
FRNK blocks v-Src-stimulated invasion and experimental metastases without effects on cell motility or growth
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_136935
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_136935
Other Identifiers
ISSN
0261-4189,1460-2075
E-ISSN
1460-2075
DOI
10.1093/emboj/cdf631
