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Parp-1 protects homologous recombination from interference by Ku and Ligase IV in vertebrate cells

Parp-1 protects homologous recombination from interference by Ku and Ligase IV in vertebrate cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1422167

Parp-1 protects homologous recombination from interference by Ku and Ligase IV in vertebrate cells

About this item

Full title

Parp-1 protects homologous recombination from interference by Ku and Ligase IV in vertebrate cells

Publisher

Chichester, UK: John Wiley & Sons, Ltd

Journal title

The EMBO journal, 2006-03, Vol.25 (6), p.1305-1314

Language

English

Formats

Publication information

Publisher

Chichester, UK: John Wiley & Sons, Ltd

More information

Scope and Contents

Contents

Parp‐1 and Parp‐2 are activated by DNA breaks and have been implicated in the repair of DNA single‐strand breaks (SSB). Their involvement in double‐strand break (DSB) repair mediated by homologous recombination (HR) or nonhomologous end joining (NHEJ) remains unclear. We addressed this question using chicken DT40 cells, which have the advantage of...

Alternative Titles

Full title

Parp-1 protects homologous recombination from interference by Ku and Ligase IV in vertebrate cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1422167

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1422167

Other Identifiers

ISSN

0261-4189

E-ISSN

1460-2075

DOI

10.1038/sj.emboj.7601015

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