Genetic and Environmental Factors Associated with Variation of Human Xenobiotic Glucuronidation and...
Genetic and Environmental Factors Associated with Variation of Human Xenobiotic Glucuronidation and Sulfation
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Author / Creator
Publisher
United States: National Institute of Environmental Health Sciences. National Institutes of Health. Department of Health, Education and Welfare
Journal title
Language
English
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Publication information
Publisher
United States: National Institute of Environmental Health Sciences. National Institutes of Health. Department of Health, Education and Welfare
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Scope and Contents
Contents
Glucuronidation and sulfation are phase 2 metabolic reactions catalyzed by large families of different isoenzymes in man. The textbook view that glucuronidation and sulfation lead to the production of harmless conjugates for simple excretion is not valid. Biologically active and toxic sulfates and glucuronides are produced and lead to adverse drug...
Alternative Titles
Full title
Genetic and Environmental Factors Associated with Variation of Human Xenobiotic Glucuronidation and Sulfation
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Author / Creator
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1470020
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1470020
Other Identifiers
ISSN
0091-6765
E-ISSN
1552-9924
DOI
10.1289/ehp.97105s4739
