Quantification of α-Synuclein Binding to Lipid Vesicles Using Fluorescence Correlation Spectroscopy
Quantification of α-Synuclein Binding to Lipid Vesicles Using Fluorescence Correlation Spectroscopy
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United States: Elsevier Inc
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Language
English
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United States: Elsevier Inc
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Contents
α-Synuclein (
αS) is a soluble synaptic protein that is the major proteinaceous component of insoluble fibrillar Lewy body deposits that are the hallmark of Parkinson’s disease. The interaction of
αS with synaptic vesicles is thought to be critical both to its normal function as well as to its pathological role in Parkinson’s disease. We demo...
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Full title
Quantification of α-Synuclein Binding to Lipid Vesicles Using Fluorescence Correlation Spectroscopy
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1471845
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1471845
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ISSN
0006-3495
E-ISSN
1542-0086
DOI
10.1529/biophysj.105.079251