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The Mechanism of Superoxide Production by NADH:Ubiquinone Oxidoreductase (Complex I) from Bovine Hea...

The Mechanism of Superoxide Production by NADH:Ubiquinone Oxidoreductase (Complex I) from Bovine Hea...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1472492

The Mechanism of Superoxide Production by NADH:Ubiquinone Oxidoreductase (Complex I) from Bovine Heart Mitochondria

About this item

Full title

The Mechanism of Superoxide Production by NADH:Ubiquinone Oxidoreductase (Complex I) from Bovine Heart Mitochondria

Author / Creator

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2006-05, Vol.103 (20), p.7607-7612

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

NADH:ubiquinone oxidoreductase (complex I) is a major source of reactive oxygen species in mitochondria and a significant contributor to cellular oxidative stress. Here, we describe the kinetic and molecular mechanism of superoxide production by complex I isolated from bovine heart mitochondria and confirm that it produces predominantly superoxide,...

Alternative Titles

Full title

The Mechanism of Superoxide Production by NADH:Ubiquinone Oxidoreductase (Complex I) from Bovine Heart Mitochondria

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1472492

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1472492

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0510977103

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