The Mechanism of Superoxide Production by NADH:Ubiquinone Oxidoreductase (Complex I) from Bovine Hea...
The Mechanism of Superoxide Production by NADH:Ubiquinone Oxidoreductase (Complex I) from Bovine Heart Mitochondria
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United States: National Academy of Sciences
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English
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United States: National Academy of Sciences
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NADH:ubiquinone oxidoreductase (complex I) is a major source of reactive oxygen species in mitochondria and a significant contributor to cellular oxidative stress. Here, we describe the kinetic and molecular mechanism of superoxide production by complex I isolated from bovine heart mitochondria and confirm that it produces predominantly superoxide,...
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Full title
The Mechanism of Superoxide Production by NADH:Ubiquinone Oxidoreductase (Complex I) from Bovine Heart Mitochondria
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1472492
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1472492
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0510977103