Gp130 Signaling in Proopiomelanocortin Neurons Mediates the Acute Anorectic Response to Centrally Ap...
Gp130 Signaling in Proopiomelanocortin Neurons Mediates the Acute Anorectic Response to Centrally Applied Ciliary Neurotrophic Factor
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Ciliary neurotrophic factor (CNTF) exerts anorectic effects by overcoming leptin resistance via activation of hypothalamic neurons. However, the exact site of CNTF action in the hypothalamus has not yet been identified. Using Cre-loxP-mediated recombination in vivo, we have selectively ablated the common cytokine signaling chain gp130, which is req...
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Full title
Gp130 Signaling in Proopiomelanocortin Neurons Mediates the Acute Anorectic Response to Centrally Applied Ciliary Neurotrophic Factor
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1502296
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1502296
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0600425103
