Noninvasive gene transfer to the lung for systemic delivery of therapeutic proteins
Noninvasive gene transfer to the lung for systemic delivery of therapeutic proteins
About this item
Full title
Author / Creator
Publisher
American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
American Society for Clinical Investigation
More information
Scope and Contents
Contents
This study evaluates the use of vectors based on adeno-associated viruses (AAVs) to noninvasively deliver genes to airway epithelial cells as a means for achieving systemic administration of therapeutic proteins. We intranasally delivered AAV vectors to mice in which the same AAV2 genome encoding a cellular marker was packaged in capsids from AAV1,...
Alternative Titles
Full title
Noninvasive gene transfer to the lung for systemic delivery of therapeutic proteins
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_150421
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_150421
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI15780
