The in vivo expression of actin/salt-resistant hyperactive DNase I inhibits the development of anti-...
The in vivo expression of actin/salt-resistant hyperactive DNase I inhibits the development of anti-ssDNA and anti-histone autoantibodies in a murine model of systemic lupus erythematosus
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England: National Library of Medicine - MEDLINE Abstracts
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Language
English
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England: National Library of Medicine - MEDLINE Abstracts
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Systemic lupus erythematosus (SLE) is characterised by the production of autoantibodies against ubiquitous antigens, especially nuclear components. Evidence makes it clear that the development of these autoantibodies is an antigen-driven process and that immune complexes involving DNA-containing antigens play a key role in the disease process. In r...
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Full title
The in vivo expression of actin/salt-resistant hyperactive DNase I inhibits the development of anti-ssDNA and anti-histone autoantibodies in a murine model of systemic lupus erythematosus
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1526614
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1526614
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ISSN
1478-6354
E-ISSN
1478-6362
DOI
10.1186/ar1936
