Rapid Evolution of Major Histocompatibility Complex Class I Genes in Primates Generates New Disease...
Rapid Evolution of Major Histocompatibility Complex Class I Genes in Primates Generates New Disease Alleles in Humans via Hitchhiking Diversity
About this item
Full title
Author / Creator
Shiina, Takashi , Ota, Masao , Shimizu, Sayoko , Katsuyama, Yoshihiko , Hashimoto, Nami , Takasu, Miwa , Anzai, Tatsuya , Kulski, Jerzy K , Kikkawa, Eri , Naruse, Taeko , Kimura, Natsuki , Yanagiya, Kazuyo , Watanabe, Atsushi , Hosomichi, Kazuyoshi , Kohara, Sakae , Iwamoto, Chie , Umehara, Yumi , Meyer, Alice , Wanner, Valerie , Sano, Kazumi , Macquin, Cecile , Ikeo, Kazuho , Tokunaga, Katsushi , Gojobori, Takashi , Inoko, Hidetoshi and Bahram, Seiamak
Publisher
United States: Genetics Soc America
Journal title
Language
English
Formats
Publication information
Publisher
United States: Genetics Soc America
Subjects
More information
Scope and Contents
Contents
A plausible explanation for many MHC-linked diseases is lacking. Sequencing of the MHC class I region (coding units or full contigs) in several human and nonhuman primate haplotypes allowed an analysis of single nucleotide variations (SNV) across this entire segment. This diversity was not evenly distributed. It was rather concentrated within two g...
Alternative Titles
Full title
Rapid Evolution of Major Histocompatibility Complex Class I Genes in Primates Generates New Disease Alleles in Humans via Hitchhiking Diversity
Authors, Artists and Contributors
Author / Creator
Ota, Masao
Shimizu, Sayoko
Katsuyama, Yoshihiko
Hashimoto, Nami
Takasu, Miwa
Anzai, Tatsuya
Kulski, Jerzy K
Kikkawa, Eri
Naruse, Taeko
Kimura, Natsuki
Yanagiya, Kazuyo
Watanabe, Atsushi
Hosomichi, Kazuyoshi
Kohara, Sakae
Iwamoto, Chie
Umehara, Yumi
Meyer, Alice
Wanner, Valerie
Sano, Kazumi
Macquin, Cecile
Ikeo, Kazuho
Tokunaga, Katsushi
Gojobori, Takashi
Inoko, Hidetoshi
Bahram, Seiamak
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1526686
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1526686
Other Identifiers
ISSN
0016-6731,1943-2631
E-ISSN
1943-2631
DOI
10.1534/genetics.106.057034
