Nociceptin receptor binding in mouse forebrain membranes: thermodynamic characteristics and structur...
Nociceptin receptor binding in mouse forebrain membranes: thermodynamic characteristics and structure activity relationships
About this item
Full title
Author / Creator
Varani, K. , Calo', G. , Rizzi, A. , Merighi, S. , Toth, G. , Guerrini, R. , Salvadori, S. , Borea, P. A. and Regoli, D.
Publisher
Oxford, UK: Blackwell Publishing Ltd
Journal title
Language
English
Formats
Publication information
Publisher
Oxford, UK: Blackwell Publishing Ltd
Subjects
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Scope and Contents
Contents
1
The present study describes the labelling of the nociceptin (NC) receptor, ORL1, in mouse forebrain membranes with a new ligand partially protected from metabolic degradation at the C‐terminal; the ligand, [3H]‐NC‐NH2, has a specific activity of 24.5 Ci mmol−1
2
Saturation experiments revealed a single class of binding sites with a KD va...
Alternative Titles
Full title
Nociceptin receptor binding in mouse forebrain membranes: thermodynamic characteristics and structure activity relationships
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1565735
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1565735
Other Identifiers
ISSN
0007-1188
E-ISSN
1476-5381
DOI
10.1038/sj.bjp.0702226