Antagonism by acetyl‐RYYRIK‐NH2 of G protein activation in rat brain preparations and of chronotropi...
Antagonism by acetyl‐RYYRIK‐NH2 of G protein activation in rat brain preparations and of chronotropic effect on rat cardiomyocytes evoked by nociceptin/orphanin FQ
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Full title
Author / Creator
Berger, H , Albrecht, E , Wallukat, G and Bienert, M
Publisher
Oxford, UK: Blackwell Publishing Ltd
Journal title
Language
English
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Publication information
Publisher
Oxford, UK: Blackwell Publishing Ltd
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Scope and Contents
Contents
For the further elucidation of the central functions of nociceptin/orphanin FQ (noc/OFQ), the endogenous ligand of the G protein‐coupled opioid receptor‐like receptor ORL1, centrally acting specific antagonists will be most helpful. In this study it was found that the hexapeptide acetyl‐RYYRIK‐NH2 (Ac‐RYYRIK‐NH2), described in literature as partial...
Alternative Titles
Full title
Antagonism by acetyl‐RYYRIK‐NH2 of G protein activation in rat brain preparations and of chronotropic effect on rat cardiomyocytes evoked by nociceptin/orphanin FQ
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1565859
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1565859
Other Identifiers
ISSN
0007-1188
E-ISSN
1476-5381
DOI
10.1038/sj.bjp.0702353
