Accelerated resequestration of cytosolic calcium and suppression of the pro‐inflammatory activities...
Accelerated resequestration of cytosolic calcium and suppression of the pro‐inflammatory activities of human neutrophils by CGS 21680 in vitro
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Author / Creator
Anderson, R , Visser, S S , Ramafi, G and Theron, A J
Publisher
Oxford, UK: Blackwell Publishing Ltd
Journal title
Language
English
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Publisher
Oxford, UK: Blackwell Publishing Ltd
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Contents
We have investigated the effects of the adenosine A2A receptor agonist CGS 21680 (0.01–1 μM) on reactive oxidant production by, and elastase release from FMLP‐activated human neutrophils, as well as on cytosolic Ca2+ fluxes and intracellular concentrations of cyclic AMP.
Oxidant production, elastase release and cyclic AMP were assayed using luci...
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Full title
Accelerated resequestration of cytosolic calcium and suppression of the pro‐inflammatory activities of human neutrophils by CGS 21680 in vitro
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1572119
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1572119
Other Identifiers
ISSN
0007-1188
E-ISSN
1476-5381
DOI
10.1038/sj.bjp.0703344