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Accelerated resequestration of cytosolic calcium and suppression of the pro‐inflammatory activities...

Accelerated resequestration of cytosolic calcium and suppression of the pro‐inflammatory activities...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1572119

Accelerated resequestration of cytosolic calcium and suppression of the pro‐inflammatory activities of human neutrophils by CGS 21680 in vitro

About this item

Full title

Accelerated resequestration of cytosolic calcium and suppression of the pro‐inflammatory activities of human neutrophils by CGS 21680 in vitro

Publisher

Oxford, UK: Blackwell Publishing Ltd

Journal title

British journal of pharmacology, 2000-06, Vol.130 (4), p.717-724

Language

English

Formats

Publication information

Publisher

Oxford, UK: Blackwell Publishing Ltd

More information

Scope and Contents

Contents

We have investigated the effects of the adenosine A2A receptor agonist CGS 21680 (0.01–1 μM) on reactive oxidant production by, and elastase release from FMLP‐activated human neutrophils, as well as on cytosolic Ca2+ fluxes and intracellular concentrations of cyclic AMP.
Oxidant production, elastase release and cyclic AMP were assayed using luci...

Alternative Titles

Full title

Accelerated resequestration of cytosolic calcium and suppression of the pro‐inflammatory activities of human neutrophils by CGS 21680 in vitro

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1572119

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1572119

Other Identifiers

ISSN

0007-1188

E-ISSN

1476-5381

DOI

10.1038/sj.bjp.0703344

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