Orphanin FQ/nociceptin and [Phe1Ψ(CH2‐NH)Gly2] nociceptin(1‐13)‐NH2 stimulate gastric motor function...
Orphanin FQ/nociceptin and [Phe1Ψ(CH2‐NH)Gly2] nociceptin(1‐13)‐NH2 stimulate gastric motor function in anaesthetized rats
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Oxford, UK: Blackwell Publishing Ltd
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Language
English
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Oxford, UK: Blackwell Publishing Ltd
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Orphanin FQ/nociceptin (OFQ/N) is a preferred endogenous ligand for the orphan opioid receptor‐like‐1 receptor. This peptide has been reported to increase intestinal, but not gastric, motor activity.
In the present study, OFQ/N (0.6–60 nmol kg−1 i.v.) increased intragastric pressure and antral contractility and, as expected, decreased blood pres...
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Full title
Orphanin FQ/nociceptin and [Phe1Ψ(CH2‐NH)Gly2] nociceptin(1‐13)‐NH2 stimulate gastric motor function in anaesthetized rats
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1572221
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1572221
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ISSN
0007-1188
E-ISSN
1476-5381
DOI
10.1038/sj.bjp.0703463