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Orphanin FQ/nociceptin and [Phe1Ψ(CH2‐NH)Gly2] nociceptin(1‐13)‐NH2 stimulate gastric motor function...

Orphanin FQ/nociceptin and [Phe1Ψ(CH2‐NH)Gly2] nociceptin(1‐13)‐NH2 stimulate gastric motor function...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1572221

Orphanin FQ/nociceptin and [Phe1Ψ(CH2‐NH)Gly2] nociceptin(1‐13)‐NH2 stimulate gastric motor function in anaesthetized rats

About this item

Full title

Orphanin FQ/nociceptin and [Phe1Ψ(CH2‐NH)Gly2] nociceptin(1‐13)‐NH2 stimulate gastric motor function in anaesthetized rats

Publisher

Oxford, UK: Blackwell Publishing Ltd

Journal title

British journal of pharmacology, 2000-08, Vol.130 (7), p.1639-1645

Language

English

Formats

Publication information

Publisher

Oxford, UK: Blackwell Publishing Ltd

More information

Scope and Contents

Contents

Orphanin FQ/nociceptin (OFQ/N) is a preferred endogenous ligand for the orphan opioid receptor‐like‐1 receptor. This peptide has been reported to increase intestinal, but not gastric, motor activity.
In the present study, OFQ/N (0.6–60 nmol kg−1 i.v.) increased intragastric pressure and antral contractility and, as expected, decreased blood pres...

Alternative Titles

Full title

Orphanin FQ/nociceptin and [Phe1Ψ(CH2‐NH)Gly2] nociceptin(1‐13)‐NH2 stimulate gastric motor function in anaesthetized rats

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1572221

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1572221

Other Identifiers

ISSN

0007-1188

E-ISSN

1476-5381

DOI

10.1038/sj.bjp.0703463

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