CB1 cannabinoid receptor antagonism promotes remodeling and cannabinoid treatment prevents endotheli...
CB1 cannabinoid receptor antagonism promotes remodeling and cannabinoid treatment prevents endothelial dysfunction and hypotension in rats with myocardial infarction
About this item
Full title
Author / Creator
Publisher
Oxford, UK: Blackwell Publishing Ltd
Journal title
Language
English
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Publication information
Publisher
Oxford, UK: Blackwell Publishing Ltd
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More information
Scope and Contents
Contents
To study the long‐term effects of altered cannabinoid receptor activity on myocardial and vascular function, Wistar rats were treated with the selective CB1 antagonist AM‐251 (0.5 mg kg−1 d−1), the potent synthetic cannabinoid HU‐210 (50 μg kg−1 d−1) or vehicle for 12 weeks after coronary artery ligation or sham operation.
AM‐251 further reduced...
Alternative Titles
Full title
CB1 cannabinoid receptor antagonism promotes remodeling and cannabinoid treatment prevents endothelial dysfunction and hypotension in rats with myocardial infarction
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1573770
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1573770
Other Identifiers
ISSN
0007-1188
E-ISSN
1476-5381
DOI
10.1038/sj.bjp.0705156
