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Effects of flecainide and quinidine on Kv4.2 currents: voltage dependence and role of S6 valines

Effects of flecainide and quinidine on Kv4.2 currents: voltage dependence and role of S6 valines

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1573805

Effects of flecainide and quinidine on Kv4.2 currents: voltage dependence and role of S6 valines

About this item

Full title

Effects of flecainide and quinidine on Kv4.2 currents: voltage dependence and role of S6 valines

Publisher

Oxford, UK: Blackwell Publishing Ltd

Journal title

British journal of pharmacology, 2003-04, Vol.138 (8), p.1475-1484

Language

English

Formats

Publication information

Publisher

Oxford, UK: Blackwell Publishing Ltd

More information

Scope and Contents

Contents

The effects of flecainide and quinidine were studied on wild‐type Kv4.2 channels (Kv4.2WT), channels with deletion of the N‐terminal domain (N‐del) and channels with mutations in the valine residues located at positions 402 and 404 in the presence (V[402,404]I) or in the absence (N‐del/V[402,404]I) of the N‐terminus.
The experiments were perform...

Alternative Titles

Full title

Effects of flecainide and quinidine on Kv4.2 currents: voltage dependence and role of S6 valines

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1573805

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1573805

Other Identifiers

ISSN

0007-1188

E-ISSN

1476-5381

DOI

10.1038/sj.bjp.0705199

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