Effects of flecainide and quinidine on Kv4.2 currents: voltage dependence and role of S6 valines
Effects of flecainide and quinidine on Kv4.2 currents: voltage dependence and role of S6 valines
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Publisher
Oxford, UK: Blackwell Publishing Ltd
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Language
English
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Oxford, UK: Blackwell Publishing Ltd
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The effects of flecainide and quinidine were studied on wild‐type Kv4.2 channels (Kv4.2WT), channels with deletion of the N‐terminal domain (N‐del) and channels with mutations in the valine residues located at positions 402 and 404 in the presence (V[402,404]I) or in the absence (N‐del/V[402,404]I) of the N‐terminus.
The experiments were perform...
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Full title
Effects of flecainide and quinidine on Kv4.2 currents: voltage dependence and role of S6 valines
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1573805
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1573805
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ISSN
0007-1188
E-ISSN
1476-5381
DOI
10.1038/sj.bjp.0705199