Different molecular sites of action for the KATP channel inhibitors, PNU‐99963 and PNU‐37883A
Different molecular sites of action for the KATP channel inhibitors, PNU‐99963 and PNU‐37883A
About this item
Full title
Author / Creator
Publisher
Oxford, UK: Blackwell Publishing Ltd
Journal title
Language
English
Formats
Publication information
Publisher
Oxford, UK: Blackwell Publishing Ltd
Subjects
More information
Scope and Contents
Contents
We investigated the mechanism of action of two novel nonsulphonylurea ATP‐sensitive potassium channel (KATP) inhibitors, PNU‐99963 and PNU‐37883A, on four types of cloned KATP channels.
Whole‐cell currents were recorded in a symmetrical potassium (140 mM) gradient in HEK‐293 cells stably expressing Kir6.2/SUR1, Kir6.2/SUR2A, Kir6.2/SUR2B or Kir6...
Alternative Titles
Full title
Different molecular sites of action for the KATP channel inhibitors, PNU‐99963 and PNU‐37883A
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1573826
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1573826
Other Identifiers
ISSN
0007-1188
E-ISSN
1476-5381
DOI
10.1038/sj.bjp.0705228
