Dihydropyridine Ca2+ channel antagonists and agonists block Kv4.2, Kv4.3 and Kv1.4 K+ channels expre...
Dihydropyridine Ca2+ channel antagonists and agonists block Kv4.2, Kv4.3 and Kv1.4 K+ channels expressed in HEK293 cells
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Oxford, UK: Blackwell Publishing Ltd
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English
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Oxford, UK: Blackwell Publishing Ltd
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We have determined the molecular basis of nicardipine‐induced block of cardiac transient outward K+ currents (Ito). Inhibition of Ito was studied using cloned voltage‐dependent K+ channels (Kv) channels, rat Kv4.3L, Kv4.2, and Kv1.4, expressed in human embryonic kindey cell line 293 (HEK293) cells.
Application of the dihydropyridine Ca2+ channel...
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Full title
Dihydropyridine Ca2+ channel antagonists and agonists block Kv4.2, Kv4.3 and Kv1.4 K+ channels expressed in HEK293 cells
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1573880
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1573880
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ISSN
0007-1188
E-ISSN
1476-5381
DOI
10.1038/sj.bjp.0705281
