TRPM2 channel opening in response to oxidative stress is dependent on activation of poly(ADP‐ribose)...
TRPM2 channel opening in response to oxidative stress is dependent on activation of poly(ADP‐ribose) polymerase
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Publisher
Oxford, UK: Blackwell Publishing Ltd
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Language
English
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Publisher
Oxford, UK: Blackwell Publishing Ltd
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Contents
TRPM2 (melastatin‐like transient receptor potential 2 channel) is a nonselective cation channel that is activated under conditions of oxidative stress leading to an increase in intracellular free Ca2+ concentration ([Ca2+]i) and cell death. We investigated the role of the DNA repair enzyme poly(ADP‐ribose) polymerase (PARP) on hydrogen peroxide (H2...
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Full title
TRPM2 channel opening in response to oxidative stress is dependent on activation of poly(ADP‐ribose) polymerase
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1575275
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1575275
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ISSN
0007-1188
E-ISSN
1476-5381
DOI
10.1038/sj.bjp.0705914
