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The pore‐forming subunit of the KATP channel is an important molecular target for LPS‐induced vascul...

The pore‐forming subunit of the KATP channel is an important molecular target for LPS‐induced vascul...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1576013

The pore‐forming subunit of the KATP channel is an important molecular target for LPS‐induced vascular hyporeactivity in vitro

About this item

Full title

The pore‐forming subunit of the KATP channel is an important molecular target for LPS‐induced vascular hyporeactivity in vitro

Publisher

Oxford, UK: Blackwell Publishing Ltd

Journal title

British journal of pharmacology, 2005-02, Vol.144 (3), p.367-375

Language

English

Formats

Publication information

Publisher

Oxford, UK: Blackwell Publishing Ltd

More information

Scope and Contents

Contents

1
ATP‐sensitive K+ (KATP) channel activation is implicated in the vascular hyporeactivity occurring in septic shock. However, channel inhibition with the sulphonylurea receptor (SUR) antagonist, glibenclamide (Glib) fails to reverse lipopolysaccharide (LPS)‐induced vascular hyporeactivity in vitro. We investigated whether inhibitors that act by...

Alternative Titles

Full title

The pore‐forming subunit of the KATP channel is an important molecular target for LPS‐induced vascular hyporeactivity in vitro

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1576013

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1576013

Other Identifiers

ISSN

0007-1188

E-ISSN

1476-5381

DOI

10.1038/sj.bjp.0706065

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