GW274150 and GW273629 are potent and highly selective inhibitors of inducible nitric oxide synthase...
GW274150 and GW273629 are potent and highly selective inhibitors of inducible nitric oxide synthase in vitro and in vivo
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Publisher
Oxford, UK: Blackwell Publishing Ltd
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Language
English
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Publisher
Oxford, UK: Blackwell Publishing Ltd
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Contents
1
GW274150 ([2‐[(1‐iminoethyl) amino]ethyl]‐L‐homocysteine) and GW273629 (3‐[[2‐[(1‐iminoethyl)amino]ethyl]sulphonyl]‐L‐alanine) are potent, time‐dependent, highly selective inhibitors of human inducible nitric oxide synthase (iNOS) vs endothelial NOS (eNOS) (>100‐fold) or neuronal NOS (nNOS) (>80‐fold). GW274150 and GW273629 are arginine compet...
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Full title
GW274150 and GW273629 are potent and highly selective inhibitors of inducible nitric oxide synthase in vitro and in vivo
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1576141
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1576141
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ISSN
0007-1188
E-ISSN
1476-5381
DOI
10.1038/sj.bjp.0706168
