Hematopoietic stem cells proliferate until after birth and show a reversible phase-specific engraftm...
Hematopoietic stem cells proliferate until after birth and show a reversible phase-specific engraftment defect
About this item
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Author / Creator
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
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Publisher
United States: American Society for Clinical Investigation
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Contents
The regulation of HSC proliferation and engraftment of the BM is an important but poorly understood process, particularly during ontogeny. Here we show that in mice, all HSCs are cycling until 3 weeks after birth. Then, within 1 week, most became quiescent. Prior to 4 weeks of age, the proliferating HSCs with long-term multilineage repopulating act...
Alternative Titles
Full title
Hematopoietic stem cells proliferate until after birth and show a reversible phase-specific engraftment defect
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1578623
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1578623
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/jci28310
