Inhibition of Na+/H+‐exchanger with sabiporide attenuates the downregulation and uncoupling of the m...
Inhibition of Na+/H+‐exchanger with sabiporide attenuates the downregulation and uncoupling of the myocardial β‐adrenoceptor system in failing rabbit hearts
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Oxford, UK: Blackwell Publishing Ltd
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Language
English
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Oxford, UK: Blackwell Publishing Ltd
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1
Chronic heart failure (HF) is characterized by left ventricular (LV) structural remodeling, impaired function, increased circulating noradrenaline (NA) levels and impaired responsiveness of the myocardial β‐adrenoceptor (βAR)‐adenylyl cyclase (AC) system. In failing hearts, inhibition of the sodium/proton‐exchanger (NHE)‐1 attenuates LV remode...
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Full title
Inhibition of Na+/H+‐exchanger with sabiporide attenuates the downregulation and uncoupling of the myocardial β‐adrenoceptor system in failing rabbit hearts
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1617059
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1617059
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ISSN
0007-1188
E-ISSN
1476-5381
DOI
10.1038/sj.bjp.0706714