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Inhibition of Na+/H+‐exchanger with sabiporide attenuates the downregulation and uncoupling of the m...

Inhibition of Na+/H+‐exchanger with sabiporide attenuates the downregulation and uncoupling of the m...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1617059

Inhibition of Na+/H+‐exchanger with sabiporide attenuates the downregulation and uncoupling of the myocardial β‐adrenoceptor system in failing rabbit hearts

About this item

Full title

Inhibition of Na+/H+‐exchanger with sabiporide attenuates the downregulation and uncoupling of the myocardial β‐adrenoceptor system in failing rabbit hearts

Publisher

Oxford, UK: Blackwell Publishing Ltd

Journal title

British journal of pharmacology, 2006-05, Vol.148 (2), p.137-146

Language

English

Formats

Publication information

Publisher

Oxford, UK: Blackwell Publishing Ltd

More information

Scope and Contents

Contents

1
Chronic heart failure (HF) is characterized by left ventricular (LV) structural remodeling, impaired function, increased circulating noradrenaline (NA) levels and impaired responsiveness of the myocardial β‐adrenoceptor (βAR)‐adenylyl cyclase (AC) system. In failing hearts, inhibition of the sodium/proton‐exchanger (NHE)‐1 attenuates LV remode...

Alternative Titles

Full title

Inhibition of Na+/H+‐exchanger with sabiporide attenuates the downregulation and uncoupling of the myocardial β‐adrenoceptor system in failing rabbit hearts

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1617059

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1617059

Other Identifiers

ISSN

0007-1188

E-ISSN

1476-5381

DOI

10.1038/sj.bjp.0706714

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