The mechanism of action of the Pseudomonas aeruginosa-encoded type III cytotoxin, ExoU
The mechanism of action of the Pseudomonas aeruginosa-encoded type III cytotoxin, ExoU
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Publisher
Chichester, UK: John Wiley & Sons, Ltd
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Language
English
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Publisher
Chichester, UK: John Wiley & Sons, Ltd
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Contents
Pseudomonas aeruginosa
delivers the toxin ExoU to eukaryotic cells via a type III secretion system. Intoxication with ExoU is associated with lung injury, bacterial dissemination and sepsis in animal model and human infections. To search for ExoU targets in a genetically tractable system, we used controlled expression of the toxin in
Saccharo...
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Full title
The mechanism of action of the Pseudomonas aeruginosa-encoded type III cytotoxin, ExoU
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_162142
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_162142
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ISSN
0261-4189,1460-2075
E-ISSN
1460-2075
DOI
10.1093/emboj/cdg290