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The mechanism of action of the Pseudomonas aeruginosa-encoded type III cytotoxin, ExoU

The mechanism of action of the Pseudomonas aeruginosa-encoded type III cytotoxin, ExoU

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_162142

The mechanism of action of the Pseudomonas aeruginosa-encoded type III cytotoxin, ExoU

About this item

Full title

The mechanism of action of the Pseudomonas aeruginosa-encoded type III cytotoxin, ExoU

Publisher

Chichester, UK: John Wiley & Sons, Ltd

Journal title

The EMBO journal, 2003-06, Vol.22 (12), p.2959-2969

Language

English

Formats

Publication information

Publisher

Chichester, UK: John Wiley & Sons, Ltd

More information

Scope and Contents

Contents

Pseudomonas aeruginosa
delivers the toxin ExoU to eukaryotic cells via a type III secretion system. Intoxication with ExoU is associated with lung injury, bacterial dissemination and sepsis in animal model and human infections. To search for ExoU targets in a genetically tractable system, we used controlled expression of the toxin in
Saccharo...

Alternative Titles

Full title

The mechanism of action of the Pseudomonas aeruginosa-encoded type III cytotoxin, ExoU

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_162142

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_162142

Other Identifiers

ISSN

0261-4189,1460-2075

E-ISSN

1460-2075

DOI

10.1093/emboj/cdg290

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