The role of the ICOS-B7h T cell costimulatory pathway in transplantation immunity
The role of the ICOS-B7h T cell costimulatory pathway in transplantation immunity
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Publisher
United States: American Society for Clinical Investigation
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Language
English
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Publisher
United States: American Society for Clinical Investigation
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Scope and Contents
Contents
Inducible costimulatory molecule (ICOS) plays a pivotal role in T cell activation and Th1/Th2 differentiation. ICOS blockade has disparate effects on immune responses depending on the timing of blockade. Its role in transplantation immunity, however, remains incompletely defined. We used a vascularized mouse cardiac allograft model to explore the r...
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Full title
The role of the ICOS-B7h T cell costimulatory pathway in transplantation immunity
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_164288
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_164288
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI200317008
