Mdm2-Dependent Ubiquitination and Degradation of the Insulin-like Growth Factor 1 Receptor
Mdm2-Dependent Ubiquitination and Degradation of the Insulin-like Growth Factor 1 Receptor
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Publisher
United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
Recently, p53 was demonstrated to affect the expression of the insulin-like growth factor 1 receptor (IGF-1R), a receptor tyrosine kinase that plays a crucial role in growth and survival of cancer cells. However, the underlying mechanisms for interaction between p53 and IGF-1R are still not fully understood. One of the challenging questions remaini...
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Full title
Mdm2-Dependent Ubiquitination and Degradation of the Insulin-like Growth Factor 1 Receptor
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_166214
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_166214
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1431613100
