Balancing Selection and the Evolution of Functional Polymorphism in Old World Monkey TRIM5α
Balancing Selection and the Evolution of Functional Polymorphism in Old World Monkey TRIM5α
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Publisher
National Academy of Sciences
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Language
English
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National Academy of Sciences
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Contents
Retroviral restriction factor TRIM5α exhibits a high degree of sequence variation among primate species. It has been proposed that this diversity is the cumulative result of ancient, lineagespecific episodes of positive selection. Here, we describe the contribution of within-species variation to the evolution of TRIM5a. Sampling within two geograph...
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Full title
Balancing Selection and the Evolution of Functional Polymorphism in Old World Monkey TRIM5α
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1679755
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1679755
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0605838103
