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Metabolic interaction between ApoE genotype and onset age in Alzheimer’s disease: implications for b...

Metabolic interaction between ApoE genotype and onset age in Alzheimer’s disease: implications for b...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1739315

Metabolic interaction between ApoE genotype and onset age in Alzheimer’s disease: implications for brain reserve

About this item

Full title

Metabolic interaction between ApoE genotype and onset age in Alzheimer’s disease: implications for brain reserve

Publisher

London: BMJ Publishing Group Ltd

Journal title

Journal of neurology, neurosurgery and psychiatry, 2005-01, Vol.76 (1), p.15-23

Language

English

Formats

Publication information

Publisher

London: BMJ Publishing Group Ltd

More information

Scope and Contents

Contents

Background: Clinically apparent Alzheimer’s disease (AD) is thought to result when brain tissue damage exceeds a critical threshold of “brain reserve”, a process possibly accelerated by the apolipoprotein E (ApoE) E4 allele. The interaction between onset age and ApoE genotype was investigated to assess whether early disease onset (<65 years) in pat...

Alternative Titles

Full title

Metabolic interaction between ApoE genotype and onset age in Alzheimer’s disease: implications for brain reserve

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1739315

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1739315

Other Identifiers

ISSN

0022-3050

E-ISSN

1468-330X

DOI

10.1136/jnnp.2003.030882

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