Metabolic interaction between ApoE genotype and onset age in Alzheimer’s disease: implications for b...
Metabolic interaction between ApoE genotype and onset age in Alzheimer’s disease: implications for brain reserve
About this item
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Author / Creator
Mosconi, L , Herholz, K , Prohovnik, I , Nacmias, B , De Cristofaro, M T R , Fayyaz, M , Bracco, L , Sorbi, S and Pupi, A
Publisher
London: BMJ Publishing Group Ltd
Journal title
Language
English
Formats
Publication information
Publisher
London: BMJ Publishing Group Ltd
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Scope and Contents
Contents
Background: Clinically apparent Alzheimer’s disease (AD) is thought to result when brain tissue damage exceeds a critical threshold of “brain reserve”, a process possibly accelerated by the apolipoprotein E (ApoE) E4 allele. The interaction between onset age and ApoE genotype was investigated to assess whether early disease onset (<65 years) in pat...
Alternative Titles
Full title
Metabolic interaction between ApoE genotype and onset age in Alzheimer’s disease: implications for brain reserve
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1739315
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1739315
Other Identifiers
ISSN
0022-3050
E-ISSN
1468-330X
DOI
10.1136/jnnp.2003.030882