Pak1 and PIX regulate contact inhibition during epithelial wound healing
Pak1 and PIX regulate contact inhibition during epithelial wound healing
About this item
Full title
Author / Creator
Publisher
Chichester, UK: John Wiley & Sons, Ltd
Journal title
Language
English
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Publication information
Publisher
Chichester, UK: John Wiley & Sons, Ltd
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Scope and Contents
Contents
Wound healing in epithelia requires coordinated cell migration and proliferation regulated by signaling mechanisms that are poorly understood. Here we show that epithelial cells expressing constitutively active or kinase‐dead mutants of the Rac/Cdc42 effector Pak1 fail to undergo growth arrest upon wound closure. Strikingly, this phenotype is only...
Alternative Titles
Full title
Pak1 and PIX regulate contact inhibition during epithelial wound healing
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_175788
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_175788
Other Identifiers
ISSN
0261-4189,1460-2075
E-ISSN
1460-2075
DOI
10.1093/emboj/cdg398
