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An essential role for Notch in neural crest during cardiovascular development and smooth muscle diff...

An essential role for Notch in neural crest during cardiovascular development and smooth muscle diff...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1783803

An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation

About this item

Full title

An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2007-02, Vol.117 (2), p.353-363

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

The cardiac outflow tract develops as a result of a complex interplay among several cell types, including cardiac neural crest cells, endothelial cells, and cardiomyocytes. In both humans and mice, mutations in components of the Notch signaling pathway result in congenital heart disease characterized by cardiac outflow tract defects. However, the s...

Alternative Titles

Full title

An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1783803

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1783803

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/jci30070

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