KCNQ4, a K+Channel Mutated in a Form of Dominant Deafness, Is Expressed in the Inner Ear and the Cen...
KCNQ4, a K+Channel Mutated in a Form of Dominant Deafness, Is Expressed in the Inner Ear and the Central Auditory Pathway
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United States: National Academy of Sciences of the United States of America
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Language
English
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United States: National Academy of Sciences of the United States of America
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Contents
Mutations in the potassium channel gene KCNQ4 underlie DFNA2, an autosomal dominant form of progressive hearing loss in humans. In the mouse cochlea, the transcript has been found exclusively in the outer hair cells. By using specific antibodies, we now show that KCNQ4 is situated at the basal membrane of these sensory cells. In the vestibular orga...
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Full title
KCNQ4, a K+Channel Mutated in a Form of Dominant Deafness, Is Expressed in the Inner Ear and the Central Auditory Pathway
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_18242
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_18242
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.97.8.4333
