Fra-1 promotes growth and survival in RAS-transformed thyroid cells by controlling cyclin A transcri...
Fra-1 promotes growth and survival in RAS-transformed thyroid cells by controlling cyclin A transcription
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Publisher
Chichester, UK: John Wiley & Sons, Ltd
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Language
English
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Publisher
Chichester, UK: John Wiley & Sons, Ltd
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Contents
Fra‐1 is frequently overexpressed in epithelial cancers and implicated in invasiveness. We previously showed that Fra‐1 plays crucial roles in
RAS
transformation in rat thyroid cells and mouse fibroblasts. Here, we report a novel role for Fra‐1 as a regulator of mitotic progression in
RAS
‐transformed thyroid cells. Fra‐1 expression and...
Alternative Titles
Full title
Fra-1 promotes growth and survival in RAS-transformed thyroid cells by controlling cyclin A transcription
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1847654
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1847654
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ISSN
0261-4189
E-ISSN
1460-2075
DOI
10.1038/sj.emboj.7601617