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Fra-1 promotes growth and survival in RAS-transformed thyroid cells by controlling cyclin A transcri...

Fra-1 promotes growth and survival in RAS-transformed thyroid cells by controlling cyclin A transcri...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1847654

Fra-1 promotes growth and survival in RAS-transformed thyroid cells by controlling cyclin A transcription

About this item

Full title

Fra-1 promotes growth and survival in RAS-transformed thyroid cells by controlling cyclin A transcription

Publisher

Chichester, UK: John Wiley & Sons, Ltd

Journal title

The EMBO journal, 2007-04, Vol.26 (7), p.1878-1890

Language

English

Formats

Publication information

Publisher

Chichester, UK: John Wiley & Sons, Ltd

More information

Scope and Contents

Contents

Fra‐1 is frequently overexpressed in epithelial cancers and implicated in invasiveness. We previously showed that Fra‐1 plays crucial roles in
RAS
transformation in rat thyroid cells and mouse fibroblasts. Here, we report a novel role for Fra‐1 as a regulator of mitotic progression in
RAS
‐transformed thyroid cells. Fra‐1 expression and...

Alternative Titles

Full title

Fra-1 promotes growth and survival in RAS-transformed thyroid cells by controlling cyclin A transcription

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1847654

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1847654

Other Identifiers

ISSN

0261-4189

E-ISSN

1460-2075

DOI

10.1038/sj.emboj.7601617

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