CD8 + T Cells in Hodgkin’s Disease Tumor Tissue Are a Polyclonal Population with Limited Clonal Expa...
CD8 + T Cells in Hodgkin’s Disease Tumor Tissue Are a Polyclonal Population with Limited Clonal Expansion but Little Evidence of Selection by Antigen
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Publisher
Bethesda, MD: Elsevier Inc
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Language
English
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Publisher
Bethesda, MD: Elsevier Inc
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Contents
A minor component (about 25%) of lymphocytes in Hodgkin’s disease (HD) are CD8
+ T cells. It is unclear whether the presence of these cells reflects an antitumor cytotoxic response. The goal of the present study was to investigate clonal composition and the T cell receptor (TCR) β repertoire of the CD8
+ T cell population in HD. Single CD8
Alternative Titles
Full title
CD8 + T Cells in Hodgkin’s Disease Tumor Tissue Are a Polyclonal Population with Limited Clonal Expansion but Little Evidence of Selection by Antigen
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1850194
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1850194
Other Identifiers
ISSN
0002-9440
E-ISSN
1525-2191
DOI
10.1016/S0002-9440(10)64528-2
