High Glucose-Induced Hypertrophy of Mesangial Cells Requires p27Kip1, an Inhibitor of Cyclin-Depende...
High Glucose-Induced Hypertrophy of Mesangial Cells Requires p27Kip1, an Inhibitor of Cyclin-Dependent Kinases
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Bethesda, MD: ASIP
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Language
English
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Bethesda, MD: ASIP
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Contents
Hypertrophy of mesangial cells is one of the earliest morphological alterations in the kidney after the onset of diabetes mellitus. We have previously shown that cultured mesangial cells exposed to high ambient glucose arrest in the G
1
phase of the cell cycle and that this is associated with an increased expression of inhibitors of the cycli...
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High Glucose-Induced Hypertrophy of Mesangial Cells Requires p27Kip1, an Inhibitor of Cyclin-Dependent Kinases
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1850372
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1850372
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ISSN
0002-9440
E-ISSN
1525-2191
DOI
10.1016/s0002-9440(10)64056-4