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High Glucose-Induced Hypertrophy of Mesangial Cells Requires p27Kip1, an Inhibitor of Cyclin-Depende...

High Glucose-Induced Hypertrophy of Mesangial Cells Requires p27Kip1, an Inhibitor of Cyclin-Depende...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1850372

High Glucose-Induced Hypertrophy of Mesangial Cells Requires p27Kip1, an Inhibitor of Cyclin-Dependent Kinases

About this item

Full title

High Glucose-Induced Hypertrophy of Mesangial Cells Requires p27Kip1, an Inhibitor of Cyclin-Dependent Kinases

Publisher

Bethesda, MD: ASIP

Journal title

The American journal of pathology, 2001-03, Vol.158 (3), p.1091-1100

Language

English

Formats

Publication information

Publisher

Bethesda, MD: ASIP

More information

Scope and Contents

Contents

Hypertrophy of mesangial cells is one of the earliest morphological alterations in the kidney after the onset of diabetes mellitus. We have previously shown that cultured mesangial cells exposed to high ambient glucose arrest in the G
1
phase of the cell cycle and that this is associated with an increased expression of inhibitors of the cycli...

Alternative Titles

Full title

High Glucose-Induced Hypertrophy of Mesangial Cells Requires p27Kip1, an Inhibitor of Cyclin-Dependent Kinases

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1850372

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1850372

Other Identifiers

ISSN

0002-9440

E-ISSN

1525-2191

DOI

10.1016/s0002-9440(10)64056-4

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