Accumulation of NFAT mediates IL-2 expression in memory, but not naïve, CD4⁺ T cells
Accumulation of NFAT mediates IL-2 expression in memory, but not naïve, CD4⁺ T cells
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
In contrast to naïve CD4⁺ T cells, memory CD4⁺ T cells rapidly express high levels of effector cytokines in response to antigen stimulation. The molecular mechanism for this specific behavior is not well understood. The nuclear factor of activated T cells (NFAT) family of transcription factors plays an important role in the transcription of many cy...
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Full title
Accumulation of NFAT mediates IL-2 expression in memory, but not naïve, CD4⁺ T cells
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1855411
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1855411
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0610442104
