An update on molecular genetics of gastrointestinal stromal tumours
An update on molecular genetics of gastrointestinal stromal tumours
About this item
Full title
Author / Creator
Publisher
London: BMJ Publishing Group Ltd and Association of Clinical Pathologists
Journal title
Language
English
Formats
Publication information
Publisher
London: BMJ Publishing Group Ltd and Association of Clinical Pathologists
Subjects
More information
Scope and Contents
Contents
Gastrointestinal stromal tumours (GISTs) are the most common primary mesenchymal tumours of the gastrointestinal tract. Most of them show activating mutations of the genes coding for KIT or platelet-derived growth factor receptor α (PDGFRα), two receptor tyrosine kinases (RTKs). The RTK inhibitor Imatinib (Gleevec®, Novartis, Switzerland), induces...
Alternative Titles
Full title
An update on molecular genetics of gastrointestinal stromal tumours
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1860404
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1860404
Other Identifiers
ISSN
0021-9746
E-ISSN
1472-4146
DOI
10.1136/jcp.2005.031112
