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Exposure of Mice to Topical Bovine Thrombin Induces Systemic Autoimmunity

Exposure of Mice to Topical Bovine Thrombin Induces Systemic Autoimmunity

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1867043

Exposure of Mice to Topical Bovine Thrombin Induces Systemic Autoimmunity

About this item

Full title

Exposure of Mice to Topical Bovine Thrombin Induces Systemic Autoimmunity

Publisher

Bethesda, MD: Elsevier Inc

Journal title

The American journal of pathology, 2001-11, Vol.159 (5), p.1957-1969

Language

English

Formats

Publication information

Publisher

Bethesda, MD: Elsevier Inc

More information

Scope and Contents

Contents

Bovine thrombin is used as an aid to hemostasis in medical and surgical procedures. At least 500,000 Americans are exposed to this therapeutic annually and reports suggest that exposure is associated with the development of autoreactive antibodies. To determine whether bovine thrombin can induce pathological autoimmunity we exposed nonautoimmune-pr...

Alternative Titles

Full title

Exposure of Mice to Topical Bovine Thrombin Induces Systemic Autoimmunity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1867043

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1867043

Other Identifiers

ISSN

0002-9440

E-ISSN

1525-2191

DOI

10.1016/S0002-9440(10)63043-X

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