Hepatocyte Transplantation into Diseased Mouse Liver : Kinetics of Parenchymal Repopulation and Iden...
Hepatocyte Transplantation into Diseased Mouse Liver : Kinetics of Parenchymal Repopulation and Identification of the Proliferative Capacity of Tetraploid and Octaploid Hepatocytes
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Bethesda, MD: ASIP
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Language
English
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Bethesda, MD: ASIP
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To examine the process of liver repopulation by transplanted hepatocytes, we developed transgenic mice carrying a mouse major urinary protein-urokinase-type plasminogen activator fusion transgene. Expression of this transgene induced diffuse hepatocellular damage beginning at 3 weeks of age, and homozygous mice supported up to 97% parenchymal repop...
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Hepatocyte Transplantation into Diseased Mouse Liver : Kinetics of Parenchymal Repopulation and Identification of the Proliferative Capacity of Tetraploid and Octaploid Hepatocytes
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1885759
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1885759
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ISSN
0002-9440
E-ISSN
1525-2191
DOI
10.1016/S0002-9440(10)64835-3